Predicting Spike Train Responses of Neuron Models Predicting Spike Train Responses of Neuron Models

Predicting spike train responses of neuron models

Parameter estimation of neuron models using in-vitro and in-vivo electrophysiological data

Spiking neuron models can accurately predict the response of neurons to somatically injected currents if the model parameters are carefully tuned. Predicting the response of in-vivo neurons responding to natural stimuli presents a far more challenging modeling problem. In this study, an algorithm is presented for parameter estimation of spiking neuron models. The algorithm is a hybrid evolution...

Integrate-and-Fire models with adaptation are good enough: predicting spike times under random current injection

Integrate-and-Fire-type models are usually criticized because of their simplicity. On the other hand, the Integrate-and-Fire model is the basis of most of the theoretical studies on spiking neuron models. Here, we develop a sequential procedure to quantitatively evaluate an equivalent Integrate-and-Fire-type model based on intracellular recordings of cortical pyramidal neurons. We find that the...

Responses of a Hodgkin-Huxley neuron to various types of spike-train inputs.

Numerical investigations have been made of responses of a Hodgkin-Huxley (HH) neuron to spike-train inputs whose interspike interval (ISI) is modulated by deterministic, semi-deterministic (chaotic), and stochastic signals. As deterministic one, we adopt inputs with the time-independent ISI and with time-dependent ISI modulated by sinusoidal signal. The Rössler and Lorentz models are adopted fo...

Poisson or Not Poisson: Differences in Spike Train Statistics between Parietal Cortical Areas

The variability of neuronal responses is proportional to the mean in many brain areas, which suggests that neural responses might follow a Poisson distribution. In this issue of Neuron, Maimon and Assad document a surprising violation of Poisson firing. Specifically, they show that there are differences in the amount of periodic structure in spike trains across cortical areas, with multimodal s...